Open AccessMulti-channel medical device for time domain functional near infrared spectroscopy based on wavelength space multiplexing
Author(s) -
Rebecca Re,
Davide Contini,
Massimo Turola,
Lorenzo Spinelli,
Lucia Zucchelli,
Matteo Caffini,
Rinaldo Cubeddu,
Alessandro Torricelli
Publication year - 2013
Publication title -
biomedical optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.362
H-Index - 86
ISSN - 2156-7085
DOI - 10.1364/boe.4.002231
Subject(s) - multiplexing , optics , detector , time domain , signal (programming language) , imaging phantom , wavelength , near infrared spectroscopy , functional near infrared spectroscopy , channel (broadcasting) , computer science , signal to noise ratio (imaging) , materials science , biomedical engineering , physics , telecommunications , medicine , computer vision , programming language , cognition , psychiatry , prefrontal cortex
We have designed a compact dual wavelength (687 nm, 826 nm) multi-channel (16 sources, 8 detectors) medical device for muscle and brain imaging based on time domain functional near infrared spectroscopy. The system employs the wavelength space multiplexing approach to reduce wavelength cross-talk and increase signal-to-noise ratio. System performances have been tested on homogeneous and heterogeneous tissue phantoms following specifically designed protocols for photon migration instruments. Preliminary in vivo measurements have been performed to validate the instrument capability to monitor hemodynamic parameters changes in the arm muscle during arterial occlusion and in the adult head during a motor task experiment.