Open AccessDynamic time domain near-infrared optical tomography based on a SPAD camera
Author(s) -
Jingjing Jiang,
Aldo Di Costanzo Mata,
Scott Lindner,
Edoardo Charbon,
Martin Wolf,
Alexander Kalyanov
Publication year - 2020
Publication title -
biomedical optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.362
H-Index - 86
ISSN - 2156-7085
DOI - 10.1364/boe.399387
Subject(s) - diffuse optical imaging , single photon avalanche diode , optics , iterative reconstruction , optical tomography , computer science , data acquisition , infrared , time domain , near infrared spectroscopy , tomography , image sensor , computer vision , physics , avalanche photodiode , detector , operating system
In many clinical applications it is relevant to observe dynamic changes in oxygenation. Therefore the ability of dynamic imaging with time domain (TD) near-infrared optical tomography (NIROT) will be important. But fast imaging is a challenge. The data acquisition of our handheld TD NIROT system based on single photon avalanche diode (SPAD) camera and 11 light sources was consequently accelerated. We tested the system on a diffusive medium simulating tissue with a moving object embedded. With 3D image reconstruction, the moving object was correctly located using only 0.2 s exposure time per source.