Feasibility of near-infrared spectroscopy as a tool for anatomical mapping of the human epicardium | Zendy

Rajinder P. SinghMoon | Zendy; Soo Young Park | Zendy; Diego M. Song Cho | Zendy; Agastya Vaidya | Zendy; Charles C. Marboe | Zendy; Elaine Y. Wan | Zendy; Christine P. Hendon | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Feasibility of near-infrared spectroscopy as a tool for anatomical mapping of the human epicardium

Author(s) -

Rajinder P. SinghMoon,

Soo Young Park,

Diego M. Song Cho,

Agastya Vaidya,

Charles C. Marboe,

Elaine Y. Wan,

Christine P. Hendon

Publication year - 2020

Publication title -

biomedical optics express

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.362

H-Index - 86

ISSN - 2156-7085

DOI - 10.1364/boe.394294

Subject(s) - ablation , adipose tissue , epicardial adipose tissue , medicine , ex vivo , endocardium , biomedical engineering , epicardial fat , cardiology , in vivo , biology , microbiology and biotechnology

Epicardial ablation is necessary for the treatment of ventricular tachycardias refractory to endocardial ablation due to arrhythmic substrates involving the epicardium. The human epicardium is composed of adipose tissue and coronary vasculature embedded on the surface and within the myocardium, which can complicate electroanatomical mapping, electrogram interpretation and ablation delivery. We propose using near-infrared spectroscopy (NIRS) to decipher adipose tissue from myocardial tissue within human hearts ex vivo . Histological measurement of epicardial adipose thickness direct correlated (R = 0.884) with the adipose contrast index. These results demonstrate the potential of NIRS integrated catheters for mapping the spatial distribution of epicardial substrates and could aid in improving guidance during epicardial ablation interventions.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research