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75-degree non-mydriatic single-volume optical coherence tomographic angiography
Author(s) -
Xiang Wei,
Tristan T. Hormel,
Yukun Guo,
Yali Jia
Publication year - 2019
Publication title -
biomedical optics express
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.362
H-Index - 86
ISSN - 2156-7085
DOI - 10.1364/boe.10.006286
Subject(s) - optics , optical coherence tomography , coherence (philosophical gambling strategy) , ghost imaging , volume (thermodynamics) , degree of coherence , degree (music) , angiography , medicine , radiology , physics , mathematics , statistics , quantum mechanics , beam (structure) , acoustics
Optical coherence tomography (OCT) and OCT angiography (OCTA) enable three-dimensional, high-resolution imaging of the eye. Yet, while they provide unprecedented structural and angiographic imaging detail, both have only limited fields of view in comparison to other imaging modalities like fundus photography. In this paper, we present a high-speed, high-sensitivity, swept source laser-based system that can acquire non-mydriatic 75-degree field of view OCT and OCTA images in a single complete scan without resorting to montaging techniques. The system uses an optimized scanning protocol and achieves capillary-level image quality. Such data may improve early detection of pathology and provide valuable information during disease monitoring.

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