Open AccessSimple adaptive mobile phone screen illumination for dual phone differential phase contrast (DPDPC) microscopy
Author(s) -
Sara Kheireddine,
Zachary J. Smith,
Dan V. Nicolau,
Sebastian WachsmannHogiu
Publication year - 2019
Publication title -
biomedical optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.362
H-Index - 86
ISSN - 2156-7085
DOI - 10.1364/boe.10.004369
Subject(s) - phone , contrast (vision) , computer science , mobile phone , optics , lens (geology) , phase (matter) , micrometer , microscope , computer vision , physics , telecommunications , philosophy , linguistics , quantum mechanics
Phase contrast imaging is widely employed in the physical, biological, and medical sciences. However, typical implementations involve complex imaging systems that amount to in-line interferometers. We adapt differential phase contrast (DPC) to a dual-phone illumination-imaging system to obtain phase contrast images on a portable mobile phone platform. In this dual phone differential phase contrast (dpDPC) microscope, semicircles are projected sequentially on the display of one phone, and images are captured using a low-cost, short focal length lens attached to the second phone. By numerically combining images obtained using these semicircle patterns, high quality DPC images with ≈ 2 micrometer resolution can be easily acquired with no specialized hardware, circuitry, or instrument control programs.