Open AccessAccuracy and precision of tissue optical properties and hemodynamic parameters estimated by the BabyLux device: a hybrid time-resolved near-infrared and diffuse correlation spectroscopy neuro-monitor
Author(s) -
Martina Giovannella,
Lorenzo Spinelli,
Marco Pagliazzi,
Davide Contini,
Gorm Greisen,
Udo M. Weigel,
Alessandro Torricelli,
Turgut Durdurán
Publication year - 2019
Publication title -
biomedical optics express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.362
H-Index - 86
ISSN - 2156-7085
DOI - 10.1364/boe.10.002556
Subject(s) - accuracy and precision , near infrared spectroscopy , optics , diffuse optical imaging , spectroscopy , correlation , noise (video) , computer science , infrared , materials science , biomedical engineering , biological system , physics , artificial intelligence , mathematics , statistics , medicine , geometry , quantum mechanics , tomography , image (mathematics) , biology
We have investigated the accuracy and precision of "the BabyLux device", a hybrid time-resolved near-infrared (TRS) and diffuse correlation spectroscopy (DCS) neuro-monitor for the pre-term infant. Numerical data with realistic noise were simulated and analyzed using the BabyLux device as a reference system and different experimental and analysis parameters. The results describe the limits for the precision and the accuracy to be expected. The dependence of these limits on different experimental conditions and choices of the analysis method is also described. Experiments demonstrate comparable values for precision with respect to the simulation results.