Accuracy and precision of tissue optical properties and hemodynamic parameters estimated by the BabyLux device: a hybrid time-resolved near-infrared and diffuse correlation spectroscopy neuro-monitor | Zendy

Martina Giovannella | Zendy; Lorenzo Spinelli | Zendy; Marco Pagliazzi | Zendy; Davide Contini | Zendy; Gorm Greisen | Zendy; Udo M. Weigel | Zendy; Alessandro Torricelli | Zendy; Turgut Durduran | Zendy

Open Access

Accuracy and precision of tissue optical properties and hemodynamic parameters estimated by the BabyLux device: a hybrid time-resolved near-infrared and diffuse correlation spectroscopy neuro-monitor

Author(s) -

Martina Giovannella,

Lorenzo Spinelli,

Marco Pagliazzi,

Davide Contini,

Gorm Greisen,

Udo M. Weigel,

Alessandro Torricelli,

Turgut Durduran

Publication year - 2019

Publication title -

biomedical optics express

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.362

H-Index - 86

ISSN - 2156-7085

DOI - 10.1364/boe.10.002556

Subject(s) - diffuse optical imaging , optics , spectroscopy , materials science , infrared , near infrared spectroscopy , correlation , biomedical engineering , nuclear magnetic resonance , physics , medicine , tomography , mathematics , geometry , quantum mechanics

We have investigated the accuracy and precision of "the BabyLux device", a hybrid time-resolved near-infrared (TRS) and diffuse correlation spectroscopy (DCS) neuro-monitor for the pre-term infant. Numerical data with realistic noise were simulated and analyzed using the BabyLux device as a reference system and different experimental and analysis parameters. The results describe the limits for the precision and the accuracy to be expected. The dependence of these limits on different experimental conditions and choices of the analysis method is also described. Experiments demonstrate comparable values for precision with respect to the simulation results.

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