Open AccessReal-time 3D thermoacoustic imaging and thermometry using a self-calibration technique
Author(s) -
Ehab Tamimi,
Hao Xin,
Russell S. Witte
Publication year - 2020
Publication title -
applied optics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.668
H-Index - 197
eISSN - 2155-3165
pISSN - 1559-128X
DOI - 10.1364/ao.393083
Subject(s) - calibration , materials science , thermocouple , mean squared error , microwave , computer science , optics , physics , mathematics , statistics , telecommunications , composite material
Thermoacoustic (TA) imaging is a modality where pulsed microwaves are used to generate ultrasound waves in tissue, which are highly correlated with temperature. This study uses a self-calibration approach to improve the estimation of temperature using 3D real-time TA thermometry in porcine tissue during localized heating. The self-calibration method estimated temperatures at eight embedded thermocouple locations with a normalized root-mean-square error of 3.25±2.08 % . The results demonstrate that the method has the suitable accuracy and resolution to provide feedback control for breast cancer ablation therapy.