Open AccessGenotoxicity evaluation of Chlorfenapyr in exposed freshwater African catfish Clarias gariepinus using micronucleus test
Author(s) -
I. K. Esenowo,
Akwaowo U. Nelson,
Chibuisi G. Alimba,
Ndifreke Daniel Ekpo,
Okeh C. Emmanuel
Publication year - 2021
Publication title -
aceh journal of animal science/aceh journal of animal science
Language(s) - English
Resource type - Journals
eISSN - 2622-8734
pISSN - 2502-9568
DOI - 10.13170/ajas.6.1.16796
Subject(s) - clarias gariepinus , chlorfenapyr , micronucleus test , genotoxicity , catfish , biology , toxicant , micronucleus , toxicology , zoology , toxicity , pesticide , ecology , fishery , fish <actinopterygii> , medicine
Chlorfenapyr is a new formulated insecticide targeted against insecticide resistant species. Its application in targeting harmful aquatic insects may potentially contaminate aquatic environment. This study is to evaluate its genotoxic effects on non-targeted aquatic biota. The study assessed the genotoxic potentials of chlorfenapyr in African catfish (Clarias gariepinus) using the micronucleus (MN) test. Juvenile stage of C. gariepinus were exposed to different concentrations; 5.00 – 15.00 mgL-1 of chlorfenapyr for 96 hours, peripheral blood was collected through the caudal vein and examined for micronucleus induction in the erythrocytes. The tested concentrations of chlorfenapyr did not elicit significant [F (5, 18) = 0.167, p 0.971] increase in MN formation and other nuclear abnormalities in the peripheral erythrocytes of C. gariepinus. The outcome of this study gives credence to the view that chlorfenapyr is not clastogenic and or aneugenic to non-targeted aquatic vertebrate with reference to fish (C. gariepinus).