Open AccessParathyromatosis: a very rare cause of recurrent primary hyperparathyroidism – case report and review of the literature
Author(s) -
Mehmet Hacıyanlı,
Serkan Karaıslı,
Gücek Haciyanli S,
Ahmet Atasever,
Arikan Etit D,
Gür Eö,
Turan Acar
Publication year - 2019
Publication title -
annals of the royal college of surgeons of england
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.39
H-Index - 63
eISSN - 1478-7083
pISSN - 0035-8843
DOI - 10.1308/rcsann.2019.0105
Subject(s) - medicine , primary hyperparathyroidism , parathyroidectomy , pathological , surgery , thyroid , hyperparathyroidism , thyroidectomy , histopathological examination , radiological weapon , radiology , parathyroid hormone , pathology , calcium
Parathyromatosis is a rare entity and usually appears as a consequence of the seeding on previous parathyroid surgery which was applied for the secondary hyperparathyroidism. A 63-year-old woman presented with a history of subtotal thyroidectomy 20 years ago and parathyroidectomy due to primary hyperparathyroidism (PHPT) four years ago. Imaging methods revealed multiple parathyromatosis foci on subcutaneous tissue of the neck. En-bloc resection was performed and pathological examination confirmed the diagnosis of parathyromatosis. After an uneventful 10 months, biochemical and radiological tests revealed recurrence on bilateral thyroid lodges. En-bloc resection was performed. The patient has remained well for 24 months after the second operation and has been followed-up with normal parathormone and serum calcium values. To the best of our knowledge, this report describes the twenty-first case of parathyromatosis in PHPT setting in the literature. It should be kept in mind that parathyromatosis may recur at different sites in the neck even in patients with PHPT.