Left Ventricular Hypertrophy dan Fungsi Ginjal pada Penderita Hipertensi

Chronic hypertension can cause complication such as left ventricular hypertrophy (LVH).  LVH can lead renal artery vasoconstriction, impaire blood perfusion to glomerulus and change glomerulus filtration coeficient. The aim of this study was to compare kidney function between hypertensive patient with LVH and without LVH Methods: This was a case control study that conducted at Dr. Moewardi General Hospital Surakarta. All subjects has been diagnosed as hypertension more than 5 years. The diagnosis of LVH was based on electrocardiography (ECG) result. Kidney function was assessed based on serum ureum, creatinin, and uric acid  levels. Results: The subject of this study was 26 hypertension patients with LVH and 13 hypertension patients without LVH. Serum ureum level in patients with LVH was higher than hypertension patients without LVH(24.92 ± 7.99 Vs 32.33±9.91, p= 0.004). Serum uric acid level in hypertension patients with LVH was higher compare to hypertension patients without LVH as well (5.26 ± 1.15 Vs 6.98 ± 1.83, p= 0.029). Whereas serum creatinine levels were not significantly different between two groups of subjects.   Sulastomo et.al., Left Ventricular Hypertrophy dan Fungsi Ginjal pada Penderita Hipertensi Conclusion: : Serum ureum and uric acid levels in hypertensive subjects with LVH are higher than subjects without LVH. There is no difference between serum creatinin level in hypertensive subject with LVH and without LVH.