Open AccessToxicity of Randia nilotica fruit extract on Schistosoma mansoni, Biomphalaria pfeifferi and Bulinus truncatus
Author(s) -
Aladdin Yousif Elteib Ebodi,
Mohammed Magzoub Ahmed
Publication year - 2017
Publication title -
cell biology and development
Language(s) - English
Resource type - Journals
ISSN - 2580-4499
DOI - 10.13057/cellbioldev/v010105
Subject(s) - schistosoma mansoni , biology , bulinus , biomphalaria , botany , toxicology , veterinary medicine , schistosomiasis , helminths , zoology , schistosoma haematobium , medicine
Ebodi AYE, Ahmed MM. 2017. Toxicity of Randia nilotica fruit extract on Schistosoma mansoni, Biomphalaria pfeifferi and Bulinus truncatus. Cell Bio Dev 1 (1): 23-30. The aqueous filtered and unfiltered extract of the fruits of Randia nilotica (locally name as Shagarat El-Murfaein) were assessed as molluscicides against Biomphalaria pfeifferi and Bulinus truncatus as well as their effect on cercariae and miracidia of Schistosoma mansoni. The plant was tested on uninfected B. pfeifferi and B. truncatus, the results showed that unfiltered extracts were found relatively more potent than filtered one (i.e. 100% was attained at 90 ppm and 80 ppm) respectively. While, filtered extract tested on uninfected B. pfeifferi and B. truncatus (100% was attained at 100 ppm and 90 ppm) respectively. The effect of unfiltered extract on infected B. pfeifferi produced 100% mortality in concentration of 70 ppm. The activity of the plant on cercariae and miracidia revealed that cercariae was more resistance than miracidia (i.e.50 ppm killed all cercariae within 3 hours while killed miracidia within 2 hours. The results were statistically analyzed and discussed, and the findings were promising and could open new avenues for the practical use of the plant at the field.