Open AccessShort Communication: Evaluation of antimicrobial activities of Alchemilla vulgaris and Portulaca oleracea ethanolic extracts and correlation with their phytochemical profiles
Author(s) -
Salem Mohamed Edrah
Publication year - 2017
Publication title -
biofarmasi
Language(s) - English
Resource type - Journals
ISSN - 1693-2242
DOI - 10.13057/biofar/f150205
Subject(s) - portulaca , phytochemical , antimicrobial , staphylococcus epidermidis , traditional medicine , agar diffusion test , candida albicans , proteus vulgaris , biology , staphylococcus aureus , chemistry , microbiology and biotechnology , food science , bacteria , botany , medicine , genetics
Edrah SM. 2017. Short Communication: Evaluation of antimicrobial activities of Alchemilla vulgaris and Portulaca oleracea ethanolic extracts and correlation with their phytochemical profiles. Biofarmasi J Nat Prod Biochem 15: 96-99. The ethanol extracts of leaves of Alchemilla vulgaris and Portulaca oleracea were studied for antimicrobial activity at 10 mg/mL concentrations by using disc diffusion method on two gram-positive bacteria: Staphylococcus aureus and Staphylococcus epidermidis; three gram-negative bacteria: Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa and one fungi: Candida albicans were used in the study. After incubation for 24 hrs, the zone of inhibition was compared with standard antibiotics Gentamycin (10 μg/disc) which was used as positive control. From the dose-dependent study, it was concluded that the ethanol extract of A. vulgaris was more potential than leave extract of P. oleracea. Almost all of the chemical ingredients present in both ethanol extracts such as tannins, flavonoids, phenols which may be responsible for the antimicrobial activity.