
Exosomes from dysfunctional chondrocytes affect osteoarthritis in Sprague-Dawley rats through FTO-dependent regulation of PIK3R5 mRNA stability
Author(s) -
Guohua Lv,
Bing Wang,
Lei Li,
Yunchao Li,
Xinyi Li,
Hanwei He,
Lei Kuang
Publication year - 2022
Publication title -
bone and joint research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.639
H-Index - 31
ISSN - 2046-3758
DOI - 10.1302/2046-3758.119.bjr-2021-0443.r2
Subject(s) - chondrocyte , exosome , chemistry , osteoarthritis , macrophage polarization , cartilage , protein kinase b , pi3k/akt/mtor pathway , autophagy , medicine , microvesicles , microbiology and biotechnology , western blot , endocrinology , macrophage , microrna , biology , signal transduction , gene , pathology , biochemistry , apoptosis , in vitro , anatomy , alternative medicine