Open AccessIdentification of mechanics-responsive osteocyte signature in osteoarthritis subchondral bone
Author(s) -
Jun Zhou,
Zhiyi He,
Jiarui Cui,
Xiaoling Liao,
Hui Cao,
Yo Shibata,
Takashi Miyazaki,
Jiaming Zhang
Publication year - 2022
Publication title -
bone and joint research
Language(s) - English
Resource type - Journals
ISSN - 2046-3758
DOI - 10.1302/2046-3758.116.bjr-2021-0436.r1
Subject(s) - osteocyte , transcriptome , osteoarthritis , biology , gene , mechanotransduction , gene expression , microbiology and biotechnology , computational biology , osteoblast , pathology , medicine , genetics , alternative medicine , in vitro
Osteoarthritis (OA) is a common degenerative joint disease. The osteocyte transcriptome is highly relevant to osteocyte biology. This study aimed to explore the osteocyte transcriptome in subchondral bone affected by OA.