Open AccessCurrent status of regenerative medicine in osteoarthritis
Author(s) -
GunIl Im
Publication year - 2021
Publication title -
bone and joint research
Language(s) - English
Resource type - Journals
ISSN - 2046-3758
DOI - 10.1302/2046-3758.102.bjr-2020-0517.r1
Subject(s) - regenerative medicine , medicine , osteoarthritis , intensive care medicine , disease , treatment modality , alternative medicine , physical therapy , stem cell , surgery , pathology , biology , genetics
The high prevalence of osteoarthritis (OA), as well as the current lack of disease-modifying drugs for OA, has provided a rationale for regenerative medicine as a possible treatment modality for OA treatment. In this editorial, the current status of regenerative medicine in OA including stem cells, exosomes, and genes is summarized along with the author’s perspectives. Despite a tremendous interest, so far there is very little evidence proving the efficacy of this modality for clinical application. As symptomatic relief is not sufficient to justify the high cost associated with regenerative medicine, definitive structural improvement that would last for years or decades and obviate or delay the need for joint arthroplasty is essential for regenerative medicine to retain a place among OA treatment methods. Cite this article: Bone Joint Res 2021;10(2):134–136.