Open AccessPatients with an increased time to treatment initiation have a poorer overall survival after definitive surgery for localized high-grade soft-tissue sarcoma in the extremity or trunk
Author(s) -
Koichi Ogura,
Tomohiro Fujiwara,
John H. Healey
Publication year - 2021
Publication title -
the bone and joint journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.587
H-Index - 181
eISSN - 2049-4408
pISSN - 2049-4394
DOI - 10.1302/0301-620x.103b6.bjj-2020-2087.r1
Subject(s) - medicine , soft tissue sarcoma , hazard ratio , proportional hazards model , soft tissue , cancer registry , sarcoma , trunk , malignancy , surgery , incidence (geometry) , cancer , pathology , confidence interval , ecology , biology , physics , optics
Time to treatment initiation (TTI) is generally defined as the time from the histological diagnosis of malignancy to the initiation of first definitive treatment. There is no consensus on the impact of TTI on the overall survival in patients with a soft-tissue sarcoma. The purpose of this study was to determine if an increased TTI is associated with overall survival in patients with a soft-tissue sarcoma, and to identify the factors associated with a prolonged TTI.