Open AccessReal-Life Data on Total Vitamin D3 (25-Hydroxyvitamin D) Concentrations in Basrah, Iraq
Author(s) -
Ibrahim Hani Hussein,
Abbas Ali Mansour,
Hussein Ali Nwayyir,
Ammar Mohammed Saeed Abdullah Almomin,
Nassar Taha Yaseen Alibrahim,
Haider Ayad Alidrisi
Publication year - 2021
Publication title -
biomedical and pharmacology journal/biomedical and pharmacology journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.191
H-Index - 18
eISSN - 2456-2610
pISSN - 0974-6242
DOI - 10.13005/bpj/2317
Subject(s) - medicine , vitamin d deficiency , vitamin d and neurology , logistic regression , univariate analysis , vitamin , multivariate analysis
Background: People from our region need a higher dose of vitamin D to maintain their serum 25(OH)D levels at concentrations greater than 20 ng/mL. This study aimed to obtain real data on vitamin D status in Basrah. Methods: Retrospective data analysis of patients seen over 2 years from May 2017 to the end of May 2019 at the Faiha Specialized Diabetes, Endocrine and Metabolism Centre (FDEMC) in Basrah, a tertiary referring center of southern Iraq. Results: The cohort included 3692 persons. Vitamin D deficiency was evident among 62.5% of the studied persons (66.5% of women and 48.7% of men). Univariate analysis for factors associated with vitamin D deficiency found it was significantly associated with female sex (OR, 2.095; 95% CI, 1.793 to 2.448; P<0.0001), age less than 44 years (OR, 2.6; 95% CI, 2.328 to 3.065; P<0.0001), nonmarried status (including single, widow and divorced) (OR, 0.768; 95% CI, 0.656 to 0.900; P<0.0001), nulliparous or unmarried status (OR, 0.684; 95% CI, 0.583 to 0.803; P<0.0001), housewife status (OR, 0.806; 95% CI, 0.673 to 0.967; P=0.020), and rural status (OR, 1.195; 95% CI, 1.034 to 1.382; P=0.016). No significant association was found between vitamin D deficiency and BMI. In multivariate logistic regression analyses, only female sex (OR, 0.513; 95% CI, 0.437 to 0.603; P<0.0001) and age less than 44 years (OR, 2.662; 95% CI, 2.252 to 3.147; P<0.0001), nulliparous or unmarried (OR, 0.814; 95% CI, 0.680 to 0.973; P=0.024) and rural residency (OR, 0.773; 95% CI, 0.647 to 0.924; P<0.0001) remained significantly associated. Conclusion: Women, a younger age, nulliparous, and a rural residency were associated with vitamin D deficiency.