Open AccessMedicinal Plants – Derived Natural Products and Phytochemical Extract as Potential Therapies for Coronavirus : Future Perspective
Author(s) -
S Rehan Ahmad
Publication year - 2021
Publication title -
biomedical and pharmacology journal/biomedical and pharmacology journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.191
H-Index - 18
eISSN - 2456-2610
pISSN - 0974-6242
DOI - 10.13005/bpj/2181
Subject(s) - coronavirus , proteases , virus , covid-19 , virology , viral life cycle , protease , pandemic , herb , natural product , drug discovery , biology , pharmacology , traditional medicine , medicine , medicinal herbs , enzyme , disease , biochemistry , viral replication , infectious disease (medical specialty) , pathology
On 11th March 2020 , the WHO has declared that the Coronavirus 2 ( SARS-CoV-2) or noval coronavirus ( COVID-19) as Global Pandemic in the whole world . Yet there is no vaccine or any kind of special treatment developed even though all the nations are testing several therapeutic molecules. Different herbs that are traditional are also being used with conventional drugs since the COVID-19 outbreak and are showing promising results in for the treatment of the patients. In this paper, we will review on the use of the natural products and its findings on how it is being used for treating and preventing the infection of COVID-19.. Only those reports were included that WHO edited in the situation. The extracts of the various herbal products and the molecules that are purified exert an anti-SARS-CoV-2 action and they inhibit the virus directly since the entry of the virus by replicating them. It is even interesting to find that some of the herb related products are able to block the C-2 receptors that are protease serine TMPRRS2. These are the proteins COVID-19 virus requires to infect the human cells. Additionally it was also seen that the that he natural products we able to inhibit proteins such as papain-like or chymotrypsin-like proteases that were required in the life cycle of the SARS-CoV-2. Hence, it is concluded that the natural products can be used in combination or alone as an alternative for preventing or treating of the novel corona virus infection.