Open AccessMelatonin in Periodontal Diseases: A Review
Author(s) -
Sankari Malaiappan,
S Meenakshi
Publication year - 2019
Publication title -
biomedical and pharmacology journal/biomedical and pharmacology journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.191
H-Index - 18
eISSN - 2456-2610
pISSN - 0974-6242
DOI - 10.13005/bpj/1607
Subject(s) - melatonin , mucositis , periodontitis , medicine , regeneration (biology) , periodontium , pharmacology , bioinformatics , dentistry , biology , microbiology and biotechnology , chemotherapy
Melatonin is a substance that is secreted by multiple organs in Humans. In addition to playing a role in the regulation of the circadian cycle, it is also known to have antioxidant, antiinflammatory, and antioncotic effects on human tissues. Oral cavity is an easy target for many conditions such as periodontitis, mucositis, cancers, and cytotoxicity from various drugs or biomaterials. Research on melatonin as a therapeutic agent has suggested that it is effective in treating the aforementioned pathologic conditions effectively. Furthermore, melatonin tends to favour bone regeneration by behaving as an osteoconductive scaffold. The aim of this review is to summarize the uses and potential of melatonin in management of periodontal diseases.