Open AccessBiodegradable Polycaprolactone Nanoparticles Based Drug Delivery Systems: A Short Review
Author(s) -
Ranjith Ramanujam,
Balraj Sundaram,
Ganesh Janarthanan,
Elamparithi Devendran,
Moorthy Venkadasalam,
M.C. John Milton
Publication year - 2018
Publication title -
biosciences biotechnology research asia/biosciences biotechnology research asia
Language(s) - English
Resource type - Journals
eISSN - 2456-2602
pISSN - 0973-1245
DOI - 10.13005/bbra/2676
Subject(s) - polycaprolactone , drug delivery , nanoparticle , bioavailability , nanotechnology , polyester , drug , materials science , pharmacology , polymer , medicine , composite material
Nanoparticles based drug delivery systems showing greater potential in various biomedical applications to deliver the drugs/bioactive molecules in controlled manner to the targeted site. Polycaprolactone, biodegradable polyester, owing its tailorable properties, various forms of polycaprolactone are used as drug carrier for a range of biomedical applications. Nanoprecipitation is a simple method to prepare the polycaprolactone nanoparticles to improve the bioavailability and therapeutic potential of various drugs/bioactive molecules. This short review focused on the preparation of polycaprolactone nanoparticles using nanoprecipitation method, nanoparticles-drug formulations and its use in various drug delivery applications.