Open AccessSevere community-acquired pneumonia caused by Leptospira interrogans: A case report and review of literature
Author(s) -
Qiu-Hong Bao,
Li Yu,
Jianjun Ding,
Yingjun Chen,
Junwei Wang,
Jian-Ming Pang,
Qi Jin
Publication year - 2021
Publication title -
world journal of clinical cases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.368
H-Index - 10
ISSN - 2307-8960
DOI - 10.12998/wjcc.v9.i8.1901
Subject(s) - leptospira interrogans , medicine , pneumonia , leptospira , community acquired pneumonia , intensive care medicine , dermatology , pathology , leptospirosis
Leptospira is an uncommon pathogen for adult severe community-acquired pneumonia and its nonspecific manifestations and limited diagnostic tests make it difficult to identify. Although conventional penicillin remains efficacious to treat leptospirosis, failure in early diagnosis and treatment can lead to progression into a deadly syndrome with multiple organ dysfunction. Next generation sequencing is of great value to understand cases with infection of unknown cause, which could help in the diagnosis of uncertain Leptospira infection.