Open AccessTraditional Chinese medicine for gait disturbance in adrenoleukodystrophy: A case report and review of literature
Author(s) -
Hyungsuk Kim,
Taeoh Kim,
Whisung Cho,
Hokyung Chang,
Won-Seok Chung
Publication year - 2021
Publication title -
world journal of clinical cases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.368
H-Index - 10
ISSN - 2307-8960
DOI - 10.12998/wjcc.v9.i31.9691
Subject(s) - medicine , gait disturbance , tinetti test , gait , physical medicine and rehabilitation , physical therapy , rating scale , electroacupuncture , timed up and go test , acupuncture , balance (ability) , alternative medicine , pathology , psychology , developmental psychology
Adrenoleukodystrophy (ALD) is caused by a deficit in the ABCD1 gene, which leads to demyelination of neurons and dysfunction of the adrenal cortices and testicles. Of the three known phenotypes, 30%-50% of male ALD patients present with the adrenomyeloneuropathy phenotype, characterized by gait disturbance as the initial symptom.