Open AccessAssociations with pancreatic exocrine insufficiency: An United Kingdom single-centre study
Author(s) -
Benjamin Shandro,
Joshua Chen,
Jennifer Ritehnia,
Andrew Poullis
Publication year - 2021
Publication title -
world journal of clinical cases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.368
H-Index - 10
ISSN - 2307-8960
DOI - 10.12998/wjcc.v9.i31.9469
Subject(s) - medicine , gastroenterology , odds ratio , pancreatitis , exocrine pancreatic insufficiency , pancreatic cancer , pancreatitis, chronic , diabetes mellitus , retrospective cohort study , cancer , endocrinology
Pancreatic exocrine insufficiency (PEI) is said to be associated with numerous conditions both within and outside the gastrointestinal (GI) system. The majority of research has been concerned with conditions that reduce the volume of functioning pancreatic tissue or prevent adequate drainage to the small bowel, such as chronic pancreatitis, cystic fibrosis, pancreatic cancer and pancreatic resection. However, the evidence base supporting an association with extra-pancreatic conditions, such as coeliac disease, diabetes mellitus and congestive cardiac failure, is heterogeneous.