Open AccessAcute myocardial infarction and extensive systemic thrombosis in thrombotic thrombocytopenic purpura: A case report and review of literature
Author(s) -
Delia Lidia Şalaru,
Cristina Andreea Adam,
Dragoș Marcu,
I Simon,
Liviu Macovei,
Lucian Ambrosie,
Elena Chiriţa,
Radu Andy Sascău,
Cristian Stătescu
Publication year - 2021
Publication title -
world journal of clinical cases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.368
H-Index - 10
ISSN - 2307-8960
DOI - 10.12998/wjcc.v9.i27.8104
Subject(s) - medicine , thrombotic thrombocytopenic purpura , thrombosis , myocardial infarction , purpura (gastropod) , cardiology , dermatology , platelet , ecology , biology
Thrombotic thrombocytopenic purpura (TTP) is a thrombotic microangiopathy characterized by the pentad of hemolytic anemia, fever, thrombocytopenia, renal failure, and neurological dysfunction. The formation of microthrombi in the arterioles and capillaries of various organs is one of the main pathophysiological mechanisms. Clinical manifestations of cardiac involvement in TTP patients are variable. Acute myocardial infarction has been reported as a complication with TTP as the secondary thrombotic event. Its emergence as the initial thrombotic event is extremely rare.