Open AccessLate-onset Leigh syndrome without delayed development in China: A case report
Author(s) -
Jing Liang,
Cuijuan Xin,
Guang-Liang Wang,
Xuemei Wu
Publication year - 2021
Publication title -
world journal of clinical cases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.368
H-Index - 10
ISSN - 2307-8960
DOI - 10.12998/wjcc.v9.i24.7133
Subject(s) - medicine , pediatrics
Leigh syndrome (LS) is one of the most common mitochondrial diseases in infants and children. LS often manifests as early-onset with delayed phenotypic development. However, late-onset LS with normal development and white matter lesions in the brain is rarely reported, thereby highlighting the phenotypic variability of LS expression.