Open AccessPsoriasis treatment using minimally manipulated umbilical cord-derived mesenchymal stem cells: A case report
Author(s) -
Hyunjun Ahn,
Sang Yeon Lee,
Won-Ju Jung,
Jia Pi,
Kye-Ho Lee
Publication year - 2021
Publication title -
world journal of clinical cases
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.368
H-Index - 10
ISSN - 2307-8960
DOI - 10.12998/wjcc.v9.i23.6798
Subject(s) - medicine , mesenchymal stem cell , umbilical cord , psoriasis , stem cell , cord lining , surgery , dermatology , pathology , adult stem cell , anatomy , embryonic stem cell , gene , biology , biochemistry , chemistry , genetics
Psoriasis is a chronic autoimmune disease that usually manifests as a red scaly epidermis, induration, and hyperproliferation of basal keratinocytes. About 2% of the world's population suffers from psoriasis but there are no clear therapeutics yet. Recently, mesenchymal stem cells (MSCs) have been regarded as a therapeutic alternative for autoimmune diseases, as they possess immunosuppressive effects without risks. Human umbilical cord-derived MSCs effectively regulate immune cells and are characterized by low immunogenicity, which has many advantages in treating immune diseases.