Open AccessHemorrhagic transformation of ischemic cerebral proliferative angiopathy: A case report
Author(s) -
Yu Xia,
Xianfeng Yu,
Zhen-Juan Ma,
Zimin Sun
Publication year - 2021
Publication title -
world journal of clinical cases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.368
H-Index - 10
ISSN - 2307-8960
DOI - 10.12998/wjcc.v9.i20.5730
Subject(s) - medicine , angiopathy , cerebral amyloid angiopathy , cardiology , diabetes mellitus , dementia , disease , endocrinology
Cerebral proliferative angiopathy (CPA) is a rare vascular disease characterized by the presence of diffuse vascular proliferation, progressive vascular hyperflow and vasodilation of multiple vessels in the normal brain parenchyma. Unlike cerebral arteriovenous malformations, CPA has a mixed appearance between that of lesions with cell proliferation and endothelial proliferation. To date, the pathogenesis of CPA is unclear, in which changes induced by cortical ischemia in the elastic layer of the blood supply artery and smooth muscle cells may be involved.