Open AccessCirculating tumor cells with epithelial-mesenchymal transition markers as potential biomarkers for the diagnosis of lung cancer
Author(s) -
Shasha Jiang,
Chun-Guo Mao,
Feng Yuan,
Bin Ji,
Shaolin Tao,
Qunyou Tan,
Bo Deng
Publication year - 2021
Publication title -
world journal of clinical cases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.368
H-Index - 10
ISSN - 2307-8960
DOI - 10.12998/wjcc.v9.i12.2721
Subject(s) - medicine , epithelial–mesenchymal transition , lung cancer , circulating tumor cell , mesenchymal stem cell , pathology , cancer research , lung , biomarker , cancer , metastasis , biology , biochemistry
Circulating tumor cells (CTCs) can be clustered into three subtypes according to epithelial-mesenchymal transition (EMT) markers: CTCs with epithelial markers (E-CTCs), CTCs with mesenchymal markers (M-CTCs), and CTCs with both markers (E&M-CTCs). CTC detection has clinical implications in the diagnosis of lung cancer (LC).