Open AccessNeutrophil gelatinase-associated lipocalin does not predict acute kidney injury in heart failure
Author(s) -
Fiorenza Ferrari,
Elisa Scalzotto,
Pasquale Esposito,
Sara Samoni,
Flavio Mistrorigo,
Lilia María Rizo Topete,
Massimo de Cal,
Grazia Maria Virzì,
Valentina Corradi,
Rossella Torregrossa,
Roberto Valle,
Stefania Bianzina,
Nadia Aspromonte,
Matteo Floris,
A Fontanelli,
Alessandra Brendolan,
Claudio Ronco
Publication year - 2020
Publication title -
world journal of clinical cases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.368
H-Index - 10
ISSN - 2307-8960
DOI - 10.12998/wjcc.v8.i9.1600
Subject(s) - medicine , acute kidney injury , acute coronary syndrome , lipocalin , renal function , cardiorenal syndrome , intensive care unit , coronary care unit , kidney disease , cardiology , cohort , renal replacement therapy , urinary system , gastroenterology , dialysis , retrospective cohort study , myocardial infarction
Acute cardiorenal syndrome type 1 (CRS-1) is defined by a rapid cardiac dysfunction leading to acute kidney injury (AKI). Neutrophil gelatinase-associated lipocalin (NGAL) is expressed on the surface of human neutrophils and epithelial cells, such as renal tubule cells, and its serum (sNGAL) and urinary have been used to predict AKI in different clinical settings.