Open AccessNovel zinc alloys for biodegradable surgical staples
Author(s) -
Hodaka Amano,
Koichi Miyake,
Akinari Hinoki,
Kazuki Yokota,
Fumie Kinoshita,
Atsuko Nakazawa,
Yujiro Tanaka,
Yasuhiro Seto,
Hiroo Uchida
Publication year - 2020
Publication title -
world journal of clinical cases
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.368
H-Index - 10
ISSN - 2307-8960
DOI - 10.12998/wjcc.v8.i3.504
Subject(s) - biocompatibility , alloy , ultimate tensile strength , metallurgy , materials science , zinc , medicine , biomedical engineering
The development of biodegradable surgical staples is desirable as non-biodegradable Ti alloy staples reside in the human body long after wound healing, which can cause allergic/foreign-body reactions, adhesion, or other adverse effects. In order to develop a biodegradable alloy suitable for the fabrication of surgical staples, we hypothesized that Zn, a known biodegradable metal, could be alloyed with various elements to improve the mechanical properties while retaining biodegradability and biocompatibility. Considering their biocompatibility, Mg, Ca, Mn, and Cu were selected as candidate alloying elements, alongside Ti, the main material of clinically available surgical staples.