Open AccessForniceal deep brain stimulation in severe Alzheimer’s disease: A case report
Author(s) -
Wei Che Lin,
Bao Wang,
Jingjie Ge,
Likun Yang,
Zhipei Ling,
Xin Xu,
Jiehui Jiang,
Chuantao Zuo,
Yuhai Wang
Publication year - 2020
Publication title -
world journal of clinical cases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.368
H-Index - 10
ISSN - 2307-8960
DOI - 10.12998/wjcc.v8.i20.4938
Subject(s) - deep brain stimulation , donepezil , medicine , neuropsychology , cognition , dementia , activities of daily living , brain stimulation , quality of life (healthcare) , cognitive decline , physical medicine and rehabilitation , neuroimaging , stimulation , disease , physical therapy , psychiatry , parkinson's disease , nursing
Forniceal deep brain stimulation (DBS) has been proposed as an alternative treatment for Alzheimer's disease (AD). Previous studies on mild to moderate AD patients demonstrated improvements in cognitive functions brought about by forniceal DBS. Here, we report our longitudinal findings in one severe AD patient for whom the activities of daily living (ADL) rather than cognitive function significantly improved after 3 mo of continuous stimulation.