Open AccessIdiopathic multicentric Castleman disease with pulmonary and cutaneous lesions treated with tocilizumab: A case report
Author(s) -
Pingyang Han,
Huihui Chi,
Yutong Su
Publication year - 2020
Publication title -
world journal of clinical cases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.368
H-Index - 10
ISSN - 2307-8960
DOI - 10.12998/wjcc.v8.i20.4922
Subject(s) - medicine , tocilizumab , parenchyma , pathology , lesion , lung , lymph node , gastroenterology , disease
Human herpes virus-8 (HHV-8)-negative, idiopathic multicentric Castleman disease (iMCD) is a rare and life-threatening disorder driven by proinflammatory cytokines, which is still poorly understood. Pulmonary parenchyma lesion is a rare condition in iMCD, which mainly manifests as lymphocytic interstitial pneumonia and is an indicator of severe iMCD. Cutaneous lesion is also very rare and mainly occurs in Asians. There have been few reports of iMCD patients with both skin and lung parenchyma involvement.