Open AccessImpact of mTOR gene polymorphisms and gene-tea interaction on susceptibility to tuberculosis
Author(s) -
Mian Wang,
Shujuan Ma,
Xinyin Wu,
Xian Zhang,
Julius Abesig,
Zhenghui Xiao,
Xin Huang,
H Yan,
Jing Wang,
Mengshi Chen,
Hongzhuan Tan
Publication year - 2020
Publication title -
world journal of clinical cases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.368
H-Index - 10
ISSN - 2307-8960
DOI - 10.12998/wjcc.v8.i19.4320
Subject(s) - medicine , gene , tuberculosis , genetics , traditional medicine , pathology , biology
mTOR gene is a key component of the PI3K/Akt/mTOR signaling pathway, and its dysregulation is associated with various diseases. Several studies have demonstrated that tea drinking is a protective factor against tuberculosis (TB). This study was designed to explore five single nucleotide polymorphisms (SNPs) of mTOR in the Han population of China to determine how their interactions with tea drinking affect susceptibility to TB.