Open AccessNeoadjuvant chemoradiotherapy for locally advanced gastric cancer with bulky lymph node metastasis: Five case reports
Author(s) -
Eiji Nomura,
Hajime Kayano,
Takashi Machida,
Izumi Hayashi,
Sachiko Yamamoto,
Akitomo Sugawara,
Masaya Mukai,
Terumitsu Hasebe
Publication year - 2020
Publication title -
world journal of clinical cases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.368
H-Index - 10
ISSN - 2307-8960
DOI - 10.12998/wjcc.v8.i18.4177
Subject(s) - medicine , radiation therapy , concomitant , cancer , regimen , chemoradiotherapy , lymph node , stage (stratigraphy) , chemotherapy , tegafur , surgery , oncology , gastroenterology , paleontology , biology
Neoadjuvant chemoradiotherapy (NACRT) has not been accepted as a general therapy for gastric cancer because of its localized effect and toxicity for radiosensitive organs. However, if radiation therapy could compensate for the limited or inadequate treatment choices available for elderly patients and/or those at high risk, the available therapeutic options for advanced gastric cancer might increase. From this perspective, we present our experiences of five patients with advanced gastric cancer in whom we used NACRT therapy with interesting results.