Open AccessAnti-N-methyl-D-aspartate-receptor antibody encephalitis combined with syphilis: A case report
Author(s) -
Xi-Yu Li,
Zhihong Shi,
Yalin Guan,
Yong Ji
Publication year - 2020
Publication title -
world journal of clinical cases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.368
H-Index - 10
ISSN - 2307-8960
DOI - 10.12998/wjcc.v8.i12.2603
Subject(s) - medicine , encephalitis , syphilis , neurosyphilis , autoimmune encephalitis , immunology , pathology , virus , human immunodeficiency virus (hiv)
Anti-N-methyl-D-aspartate-receptor (NMDAR) encephalitis is a common type of autoimmune encephalitis characterized by complex clinical signs and variable imaging manifestations. The pathogenesis of the disease is unclear. Syphilis is an infectious disease caused by Treponema pallidum that can invade the nervous and immune systems and cause systemic symptoms. There are few reports of anti-NMDAR encephalitis with syphilis, and the association between them is unknown; both diseases are related to immune system damage. We report a case of anti-NMDAR encephalitis with syphilis.