Open AccessClinical prediction of complicated appendicitis: A case-control study utilizing logistic regression
Author(s) -
Yasutsuna Sasaki,
Fumiya Komatsu,
Naoyasu Kashima,
Takeshi Suzuki,
Ikutaka Takemoto,
Sho Kijima,
Tadashi Maeda,
Taito Miyazaki,
Yoshiaki Honda,
Hiroaki Zai,
Nagato Shimada,
Kimihiko Funahashi,
Yoshihisa Urita
Publication year - 2020
Publication title -
world journal of clinical cases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.368
H-Index - 10
ISSN - 2307-8960
DOI - 10.12998/wjcc.v8.i11.2127
Subject(s) - medicine , appendicitis , univariate analysis , logistic regression , anorexia , surgery , multivariate analysis
Since high-quality evidence on conservative treatment of acute appendicitis using antibiotics has increased, differentiation of patients with complicated appendicitis (CA) from those with simple appendicitis (SA) has become increasingly important. Previous studies have revealed that male gender, advanced age, comorbid conditions, prehospital delay, fever, and anorexia are risk factors of perforated appendicitis. Elevated serum C-reactive protein (CRP) level and hyponatremia have also been reported as predictive biomarkers of CA. However, confounding between various factors is problematic because most previous studies were limited to univariate analysis.