Open AccessBilateral adrenocortical adenomas causing adrenocorticotropic hormone-independent Cushing’s syndrome: A case report and review of the literature
Author(s) -
Yulin Gu,
Weijun Gu,
Jingtao Dou,
Zhao-hui Lv,
Jie Li,
Saichun Zhang,
Guoqing Yang,
Qinghua Guo,
Jianming Ba,
Li Zang,
Nan Jin,
Jin Du,
Pei Yu,
Yiming Mu
Publication year - 2019
Publication title -
world journal of clinical cases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.368
H-Index - 10
ISSN - 2307-8960
DOI - 10.12998/wjcc.v7.i8.961
Subject(s) - medicine , adrenocorticotropic hormone , dexamethasone suppression test , endocrinology , dexamethasone , adenoma , cushing syndrome , metyrapone , adrenal cortex , hormone
Adrenocorticotropic hormone (ACTH)-independent Cushing's syndrome (CS) is mostly due to unilateral tumors, with bilateral tumors rarely reported. Its common causes include primary pigmented nodular adrenocortical disease, ACTH-independent macronodular adrenal hyperplasia, and bilateral adrenocortical adenomas (BAAs) or carcinomas. BAAs causing ACTH-independent CS are rare; up to now, fewer than 40 BAA cases have been reported. The accurate diagnosis and evaluation of BAAs are critical for determining optimal treatment options. Adrenal vein sampling (AVS) is a good way to diagnose ACTH-independent CS.