Open AccessInteraction of arylsulfatases A and B with maspin: A possible explanation for dysregulation of tumor cell metabolism and invasive potential of colorectal cancer
Author(s) -
Zsolt Kovács,
Ioan Jung,
Krisztina Szalman,
Laura Banias,
Tivadar Bara,
Simona Gurzu
Publication year - 2019
Publication title -
world journal of clinical cases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.368
H-Index - 10
ISSN - 2307-8960
DOI - 10.12998/wjcc.v7.i23.3990
Subject(s) - maspin , medicine , tumor budding , carcinogenesis , immunohistochemistry , colorectal cancer , cancer , cancer research , pathology , gene expression , oncology , metastasis , gene , lymph node metastasis , biology , biochemistry
Although it has been shown that arylsulfatases are lost in colorectal cancer (CRC) cell lines, their exact role in the carcinogenesis and behavior of this cancer was not elucidated. No data about the correlation between serum and immunohistochemical (IHC) level of arylsulfatases (ARSA, ARSB) in patients with CRC were published yet.