Open AccessCharacterization of microbiota in systemic-onset juvenile idiopathic arthritis with different disease severities
Author(s) -
Yujie Dong,
Wei Wang,
Ji Li,
Ming Ma,
Leilei Zhong,
Qijiao Wei,
Hongmei Song
Publication year - 2019
Publication title -
world journal of clinical cases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.368
H-Index - 10
ISSN - 2307-8960
DOI - 10.12998/wjcc.v7.i18.2734
Subject(s) - medicine , arthritis , firmicutes , dysbiosis , bacteroidetes , juvenile , disease , gastroenterology , bacteria , biology , 16s ribosomal rna , genetics
Systemic-onset juvenile idiopathic arthritis (SoJIA) is one of most serious subtypes of juvenile idiopathic arthritis. Although the pathogenesis of SoJIA remains unclear, several studies have suggested a correlation between gut dysbiosis and JIA. Further understanding of the intestinal microbiome may help to establish alternative ways to treat, or even prevent, the disease.