Open AccessLiver failure associated with benzbromarone: A case report and review of the literature
Author(s) -
Mingyuan Zhang,
Junqi Niu,
Xiaoyu Wen,
Qinglong Jin
Publication year - 2019
Publication title -
world journal of clinical cases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.368
H-Index - 10
ISSN - 2307-8960
DOI - 10.12998/wjcc.v7.i13.1717
Subject(s) - benzbromarone , medicine , hyperuricemia , hepatic encephalopathy , sofosbuvir , gastroenterology , gout , uric acid , surgery , cirrhosis , immunology , ribavirin , hepatitis c virus , virus
Benzbromarone is a uricosuric agent that reduces proximal tubular reabsorption of uric acid. Because of hepatotoxicity, it has been withdrawn from the market in Europe. Recently, some benefit-risk assessments of benzbromarone suggest that benzbromarone has greater benefits than risks, and the application of benzbromarone in the treatment of gout and hyperuricemia is still under debate.