Open AccessSynchronous multiple primary gastrointestinal cancers with CDH1 mutations: A case report
Author(s) -
Mu-Ni Hu,
Wei Lv,
Rui-Yue Hu,
Yi-Fan Si,
Xiaowen Lu,
Yan-Juan Deng,
Huan Deng
Publication year - 2019
Publication title -
world journal of clinical cases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.368
H-Index - 10
ISSN - 2307-8960
DOI - 10.12998/wjcc.v7.i13.1703
Subject(s) - cdh1 , medicine , signet ring cell carcinoma , colorectal cancer , pathology , signet ring cell , carcinogenesis , pathological , wnt signaling pathway , cancer , cancer research , cadherin , gene , cell , adenocarcinoma , biology , genetics
Synchronous multiple primary cancers (SMPC) mean two or more malignant tumors occurring simultaneously and with different origins no matter what types they are or where they are located. The carcinogenesis of SMPC often involves variations of some specific genes. However, the correlation between CDH1 mutations and synchronous multiple primary gastrointestinal cancers is largely unknown.