Open AccessFull-term pregnancy in breast cancer survivor with fertility preservation: A case report and review of literature
Author(s) -
Marta Garrido-Marín,
Pedro Maria Argacha,
Luís Fernández,
Florencia Molfino,
Fina MartínezSoler,
Avelina Tortosa,
Pepita GiménezBonafé
Publication year - 2019
Publication title -
world journal of clinical cases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.368
H-Index - 10
ISSN - 2307-8960
DOI - 10.12998/wjcc.v7.i1.58
Subject(s) - medicine , breast cancer , hydrosalpinx , pregnancy , gynecology , fertility preservation , breastfeeding , obstetrics , endometriosis , infertility , endometrium , fertility , cancer , pathology , population , environmental health , biology , genetics
A 43-year-old woman with an associated history of gynecological pathology and breast cancer with only one cryopreserved embryo wished to be a mother. Several factors that influenced the success of the pregnancy in this case were analyzed. Favorable factors included: triple positive breast cancer [positive hormone receptors and positive human epidermal growth factor receptor 2], which is more hormosensitive and chemosensitive; absence of metastasis; correct endometrium preparation; and the patient's optimistic attitude and strict health habits. In contrast, the factors against success were: breast cancer; adjuvant breast cancer therapy gonadotoxicity; the age of the patient (> 40-year-old); endometriosis; ovarian cyst; hydrosalpinx; submucosal fibroids and the respective associated surgery done for the above-mentioned pathology (all resolved prior to the embryo transfer); and a low quantity of ovules (low ovarian reserve) after ovarian stimulation. This is a very special clinical case of a patient with theoretically low pregnancy success probability due to the consecutive accumulation of gynecological and oncological pathologies, who nonetheless became pregnant and delivered a full-term infant and was able to provide adequate breastfeeding.