Open AccessRenal cell carcinoma presented with a rare case of icteric Stauffer syndrome: A case report
Author(s) -
Dimitar R Popov,
Krasimir Antonov,
Evelina G Atanasova,
Christo P Pentchev,
Lyuben M Milatchkov,
Maria D Petkova,
Krasimir G Neykov,
Rosen K Nikolov
Publication year - 2022
Publication title -
world journal of clinical cases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.368
H-Index - 10
ISSN - 2307-8960
DOI - 10.12998/wjcc.v10.i25.9087
Subject(s) - medicine , cholestasis , malignancy , jaundice , gastroenterology , renal cell carcinoma , differential diagnosis , pathology
Paraneoplastic syndromes remain poorly understood and manifest as multifaceted clinical symptoms, making their diagnosis difficult. Cholestasis can be observed in various malignancies. In rare cases, it can be a paraneoplastic manifestation, most often associated with renal cell carcinoma and other urogenital tumors, as well as with bronchial carcinoma. The classical form of Stauffer syndrome presents with a reversible anicteric increase of cholestatic liver function tests, thrombocytosis, coagulation impairment, and hepatosplenomegaly, without any proven hepatobiliary obstruction or metastases.