Open AccessIntra-abdominal ectopic bronchogenic cyst with a mucinous neoplasm harboring a GNAS mutation: A case report
Author(s) -
Takashi Murakami,
Hiroaki Shimizu,
Kazuto Yamazaki,
Hiroyuki Nojima,
Akihiro Usui,
Chihiro Kosugi,
Kiyohiko Shuto,
Shuntaro Obi,
Takahisa Sato,
Masato Yamazaki,
Keiji Koda
Publication year - 2022
Publication title -
world journal of clinical cases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.368
H-Index - 10
ISSN - 2307-8960
DOI - 10.12998/wjcc.v10.i24.8709
Subject(s) - medicine , gnas complex locus , bronchogenic cyst , pathology , cyst , carcinoembryonic antigen , malignancy , cancer , biology , biochemistry , gene
Bronchogenic cysts are congenital cysts caused by abnormal sprouting from the ventral foregut during fetal life. They usually occur in the mediastinum or lung, but there are very rare cases of ectopic bronchogenic cysts that develop in the abdominal cavity. A unique intra-abdominal ectopic bronchogenic cyst with a mucinous neoplasm that was producing carcinoembryonic antigen (CEA), harboring a GNAS mutation, is reported. The present case may contribute to clarifying the mechanism of tumorigenesis and malignant transformation of ectopic bronchogenic cysts.