Open AccessEpstein–Barr-virus-associated hepatitis with aplastic anemia: A case report
Author(s) -
Wanjun Zhang,
Liqiang Wu,
Jun Wang,
Lin Shen,
Bo Wang
Publication year - 2022
Publication title -
world journal of clinical cases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.368
H-Index - 10
ISSN - 2307-8960
DOI - 10.12998/wjcc.v10.i23.8242
Subject(s) - medicine , eltrombopag , aplastic anemia , jaundice , hepatitis , gastroenterology , fulminant hepatitis , elevated transaminases , anemia , regimen , fulminant , immunology , bone marrow , antibody , immune thrombocytopenia
Hepatitis-associated aplastic anemia (HAAA) is a rare condition. Patients with HAAA usually present with acute hepatitis, jaundice and significantly increased transaminase. After 1-2 mo, hepatitis gradually improves, but progressive hemocytopenia, bone marrow hematopoietic failure, and severe or extremely severe aplastic anemia are manifest. Most cases of HAAA are fulminant and usually lethal if left untreated. The literature on Epstein-Barr virus (EBV)-associated HAAA is sparse.