Open AccessCorticosteroid-induced bradycardia in multiple sclerosis and maturity-onset diabetes of the young due to hepatocyte nuclear factor 4-alpha mutation: A case report
Author(s) -
Sung-Yeon Sohn,
Shin Yeop Kim,
In Soo Joo
Publication year - 2022
Publication title -
world journal of clinical cases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.368
H-Index - 10
ISSN - 2307-8960
DOI - 10.12998/wjcc.v10.i21.7415
Subject(s) - medicine , methylprednisolone , bradycardia , sinus bradycardia , corticosteroid , discontinuation , diabetes mellitus , gastroenterology , anesthesia , endocrinology , heart rate , blood pressure
Intravenous steroid pulse therapy is the treatment of choice for acute exacerbation of multiple sclerosis (MS). Although steroid administration is generally well-tolerated, cases of cardiac arrhythmia have been reported. Herein, we describe a young woman who developed marked sinus bradycardia and T-wave abnormalities after corticosteroid administration. We also present plausible explanations for the abnormalities observed in this patient.