Open AccessPulmonary lymphomatoid granulomatosis in a 4-year-old girl: A case report
Author(s) -
Jiawei Yao,
Qiu Li,
Ping Liang,
Hanmin Liu,
Lina Chen
Publication year - 2022
Publication title -
world journal of clinical cases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.368
H-Index - 10
ISSN - 2307-8960
DOI - 10.12998/wjcc.v10.i16.5380
Subject(s) - medicine , lymphomatoid granulomatosis , pathology , cd30 , lymphoma , lung biopsy , biopsy
Pulmonary lymphomatoid granulomatosis (PLG) is a lymphoproliferative disease associated with Epstein-Barr viral infection occurring mainly in adults and rarely in children. It is characterized by multiple pulmonary nodules. Its diagnosis depends on lung biopsy findings. Most patients are immunodeficient, and it commonly presents in children undergoing chemotherapy for leukemia. We report the case of a child with PLG caused by a mutation in the macrophage-expressed gene 1 (MPEG1), suggesting possible PLG occurrence in children undergoing treatment for pulmonary nodular lesions.