Open AccessDiagnosis of cytomegalovirus encephalitis using metagenomic next-generation sequencing of blood and cerebrospinal fluid: A case report
Author(s) -
Chi Xu,
Xia-Ling Chen,
Dongsheng Zhang,
Jiawei Wang,
Hong Yan,
Wei-Fan Chen,
Han Xia,
Zhong-Yin Zhang,
Fuhua Peng
Publication year - 2022
Publication title -
world journal of clinical cases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.368
H-Index - 10
ISSN - 2307-8960
DOI - 10.12998/wjcc.v10.i14.4601
Subject(s) - medicine , encephalitis , status epilepticus , cerebrospinal fluid , cytomegalovirus , population , viral encephalitis , autoimmune encephalitis , virology , immunology , pathology , epilepsy , viral disease , virus , herpesviridae , environmental health , psychiatry
Cytomegalovirus (CMV) infections in the population are mostly subclinical, inapparent, or latent. However, it is rare in brain tissue. Most reported CMV encephalitis cases were patients with immunodeficiency. The diagnosis and detection rate of CMV encephalitis in patients with normal immune function needs to be further improved.