Open AccessFungi as chemical industries and genetic engineering for the production of biologically active secondary metabolites
Author(s) -
Abid Ali Khan,
Nafees Bacha,
Bashir Ahmad,
Ghosia Lutfullah,
Umar Farooq,
Russell J. Cox
Publication year - 2014
Publication title -
asian pacific journal of tropical biomedicine/asian pacific journal of tropical biomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.507
H-Index - 61
eISSN - 2588-9222
pISSN - 2221-1691
DOI - 10.12980/apjtb.4.2014apjtb-2014-0230
Subject(s) - secondary metabolite , secondary metabolism , heterologous , industrial microbiology , metabolic engineering , biology , microbiology and biotechnology , biological activity , chemistry , biochemical engineering , biochemistry , computational biology , biosynthesis , enzyme , gene , fermentation , in vitro , engineering
Fungi is somewhere in between the micro and macro organisms which is a good source of producing biologically active secondary metabolites. Fungi have been used as tool for producing different types of secondary metabolites by providing different nutrients at different laboratory conditions. The fungi have been engineered for the desired secondary metabolites by using different laboratory techniques, for example, homologous and heterologous expressions. This review reported how the fungi are used as chemical industry for the production of secondary metabolites and how they are engineered in laboratory for the production of desirable metabolites; also the biosynthetic pathways of the bio-organic-molecules were reported