Open AccessTHE IMMUNE RESPONSE AGAINST RABIES VIRUS AMONG CANINE DONORS IN A ROMANIAN BLOOD BANK
Author(s) -
T Ionescu,
Marius Dan,
D. Cobzariu,
Stelian Bărăităreanu,
Doina Daneş
Publication year - 2021
Publication title -
proceedings of cbu in medicine and pharmacy ...
Language(s) - English
Resource type - Journals
eISSN - 2695-074X
pISSN - 2695-0731
DOI - 10.12955/pmp.v2.172
Subject(s) - rabies , rabies virus , medicine , blood donor , immune system , blood bank , immune status , antibody , veterinary medicine , immunology , virology , emergency medicine
Seventy-six samples were collected from sixteen canine blood donors at every blood donation performed in accord with the canine donor selection guidelines. Statistical analysis of ELISA OD values revealed no significant variation of anti-rabies antibodies values during repeat donations. Our results support the statement that blood donation does not affect the immune status of donors.
OBJECTIVES: The study aimed to assess the immune status against rabies among the canine blood donors in a Romanian canine blood bank
METHODS: Serum samples (n=76) were collected from pet owned dogs (n=16) recorded in the blood bank register of a Romanian blood bank were performed with the immunological status of the investigated canine blood donors was evaluated using the indirect ELISA commercial kit PLATELIA RABIES II (BIO-RAD, France) as per the manufacturer's instructions
RESULTS: The overall picture of ELISA OD results revealed non-significant variation between and within D1-D6 groups of values (p>0.05, F<Fcrit).
CONCLUSION: The next studies topic would be to compare the results provided by the ELISA technology with FAVN.